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Webinar: Introducing SENSOCELL

Webinar: Introducing SENSOCELL

 

Introducing SENSOCELL: Optical Tweezers for Mechanobiology

📅DATE: October 22, 2020
⌚Time: 19h CET (Paris, GMT+2)

SENSOCELL is an optical tweezers system, designed for mechanobiology studies in living cells and 3D tissues. It allows manipulating and deforming cells as whole or even endogenous structures such as the cell membrane, the cell nucleus, vesicles and other organelles while tracking the in vivo biological forces involved thanks to its unique direct force sensor technology.

SENSOCELL can be used for challenging cell studies such as: cell micro-rheology, nucleus mechanotransduction, cell membrane mechanics, molecular motor activity and cell-cell interactions and many more. More information about the system and its applications can be found on our website.

In this webinar we will introduce the system, answer your questions and show some application examples including the latest data acquired with SENSOCELL on microrheology and cells nucleus indentation tests. The webinar will last 45 minutes.

The webinar will be conducted and presented by:

  • Oriol Nos Aguila, PhD – CEO at Impetux
  • Vincent Renaud, MSc – Sales Application Engineer at Axiom Optics
  • Nese Didem Temeltas, MSc – Sales Application Engineer at Axiom Optics

 

Who should attend this webinar ?

Scientists and researchers interested specialized in cell mechanobiology or single-molecule studies or just curious scientists interested in optical tweezing and manipulating really small things.

We are looking forward to your attendance.

 

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More news:

Fig. 1

Time dependence of trap position (top), force signal (middle) and Ca2+ fluorescence signal (bottom) recorded during a membrane tether pulling experiment. The force and Ca2+ ion channel activity signals exhibit negative correlation.

Fig. 2

Force and displacement data for two beads stimulated at frequencies of 4 Hz and 0.25 Hz. The progressive reduction of the beads displacement is in concomitancy with an increase of the applied force and loading rate.

Fig. 1

Schematic representation of the optical tweezers experiment. A fibronectin-coated bead is trapped, brought into contact with the cell membrane and stimulated with oscillations at different frequencies.

Fig.2

Time dependence of trap 1 and trap 2 position (top) and force (bottom) data along the different steps of the described dual tether pulling experiment.

Fig.1

Confocal video of the described dual tether pulling assay performed on a neuron axon. Courtesy of M. Krieg lab (ICFO).

Fig. 1

Time dependence of trap position (top), force signal (middle) and Ca2+ fluorescence signal (bottom) recorded during a membrane tether pulling experiment. The force and Ca2+ ion channel activity signals exhibit negative correlation.

Video 1

Confocal video showing a DVA neuron Ca2+ ion channel activity in a dynamic optical trapping assay. The pulling rate applied to the membrane tether is progressively increased. Scale bar = 5µm. Acquired at 10Hz.