A novel optical tweezers concept for cell and tissue mechanobiology.

A unique Force sensor technology:

 

  • No calibrations needed.
  • Measure forces inside living cells and tissues.
  • Simultaneous measurements on multiple traps.
  • Measure on non-spherical objects.
  • 3D Force measurements.

Multiple optical traps generation module:

 

  • Up to 256 traps.
  • AOD beam steering technology.
  • 25 kHz trap steering frequency.
  • 5W, 1064 nm single-frequency laser.
  • Compatible with different microscopies (BF, epi-FL, DIC, TIRFF, Confocal…).

Automated routines for cell mechanobiology:

 

  • “Click and Drag” trapping mode.
  • Active & passive micro-rheology.
  • Tether pulling & escape force measurements.
  • Multiple particles oscillations & trajectories definition.
  • Force clamp mode.
  • Trap stiffness & position calibration… and more coming soon!
  • Create your own routines using our LightAce macro language!

SENSOCELL™ – Optical tweezers for mechanobiology

Specially designed for mechanobiology applications, the distinctive optical tweezers technology developed and commercialized by IMPETUX enables unprecedented experiments in cells and 3D tissues:

  • Perform multiple optical trapping experiments with simultaneous force measurements and active/passive micro-rheology tests inside living cells or 3D tissues.
  • Manipulate individual cells or cell organelles like nuclei, membranes or other native structures while tracking the forces involved in a non-invasive way.

Main features:

  • Up to 256 optical traps.
  • Calibration-free force measurements in living cells and 3D tissues.
  • Compatible with phase contrastDIC or fluorescence imaging.
  • Active/passive micro-rheology measurements of biological samples.
  • Ease of use and user friendly control software interface.
  • Automated routines for cell mechanobiology studies: Force clamp, tether pulling…
  • Create your own routines using our simple macro language.
  • Accurate determination of sample position.
  • Optimal trapping efficiency* to prevent cell damage.
  • Maximum control of laser power at sample.

* Factor 2-3 compared to traditional technology.

Jump to System Description

Request a quote or

contact us for more information.

Video Demonstrations


Basic features

overview


Trap generation and manipulation
Calibration-free force measurements
Oscillation routines
Power spectra acquisition
Active & passive micro-rheology

Particle Manipulation &

Force measurements


Optical trap generation
Particle manipulation
Calibration-free force measurements

Applications

Overview


Cell manipulation
Cell adhesion forces
Cell-cell interactions
Tether pulling
Cell stretching
Ative & passive micro-rheology

System Description


SENSOCELL™ is and add-on instrument for Nikon inverted microscopes. It can be either installed on a preexisting microscope or offered by us in an integrated platform including a new Nikon Ti-2 inverted microscope. The optical tweezers platform is composed by:

  • An optical manipulation module allowing optical trapping and manipulation of multiple microscopic samples.
  • A force sensor module allowing simultaneous & direct measurement of the exerted optical trapping forces.
  • A rack mount case with all electronics and a single-frequency laser source (5W, 1064 nm).

SENSOCELL™  also comes with LightAce, its powerful, flexible and user-friendly control software suite featuring:

  • Extensive control over multiple simultaneous optical traps.
  • Force & position real time data analysis for multiple optical traps.
  • Predefined and customizable automated routines for cell mechanobiology applications.
  • The possibility of creating your own routines using a simple and flexible macro language.

All our systems are aligned at our customer’s lab to assure optimal performance. After installation, an intensive training course is offered by our expert technicians.

Contact us:

impetux@impetux.com

(+34) 93 185 69 38

Visit us:

Mallorca 93 | 08029 Barcelona

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