The world-wide patented technology* developed by our scientific team, and incorporated in our optical tweezers systems, has been scientifically validated by external and independent leading researchers mainly in Europe and US:
US Patent 8,637,803 (2014).
JP Patent 5,728,470 (2015).
EP Patent 2,884,325 (2017).
EP Patent 2,442,316 (pending).
” Recent developments in the field are moving toward obtaining direct force measurements by detecting light momentum changes. “
D. Craig et al., ACS Photonics, 2015
“ This makes the direct force measurement method a prime choice, e.g., for in vivo measurements in biological samples. ”
G. Thalhammer et al., Opt. Express, 2015
“ With the ultimate goal of making well-calibrated force measurements in vivo, we compared three different calibration methods. Ultimately, we favor the momentum-change approach, which is easier to implement. ”
Y. Jun et al., Biophys. J., 2014
“ The light momentum method has significant advantages, as the calibration performed in water remains valid regardless of the media in which the measurement is performed. ”
A. G. Hendricks and Y. E. Goldman, Optical Tweezers: Methods and Protocols, 2017
Some of the published scientific articles:
- Xing Ma, Anita Jannasch, Urban-Raphael Albrecht, Kersten Hahn, Albert Miguel-López, Erik Schäffer, and Samuel Sánchez. “Enzyme-Powered Hollow Mesoporous Janus Nanomotors”. Nano Lett., 15 (10), pp 7043–7050, (2015).
- Michael A. Taylor, Muhammad Waleed, Alexander B. Stilgoe, Halina Rubinsztein-Dunlop and Warwick P. Bowen. “Enhanced optical trapping via structured scattering“. Nature Photonics 9,669–673 (2015)
- Gregor Thalhammer, Lisa Obmascher, and Monika Ritsch-Marte, “Direct measurement of axial optical forces“.Optics Express, Vol. 23, Issue 5, pp. 6112-6129 (2015)
- Y. Jun, S.K. Tripathy, B.R.J. Narayanareddy, M. K. Mattson-Hoss, S.P. Gross, “Calibration of Optical Tweezers for In Vivo Force Measurements: How do Different Approaches Compare?”. Biophysical Journal, V 107, 1474-1484 (2014).