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Webinar on Microrheology with SENSOCELL

Webinar on Microrheology with SENSOCELL

Join Our Upcoming Webinar on Microrheology with SENSOCELL Optical Trap

We are pleased to announce that on February 26, 2025, from 10:00 to 11:00 AM (CET), the Imaging and Optics Facility (IOF) at Institute of Science and Technology Austria will host a remote seminar on microrheology using our SENSOCELL optical trapping system.

The seminar will be led by Dr. Frederic Català-Castro, Applications Scientist at IMPETUX.

During the session, he will present several biological applications of the TimSOM technique, a method based on single-laser optical tweezers for active microrheology. This technique enables precise measurements of the viscoelastic properties of protein condensates, as well as the cytoplasm and nucleus of living cells.

This is a great opportunity to discover how SENSOCELL can advance research in mechanobiology and related fields.

Join the seminar here

For more details about SENSOCELL and its applications, visit our product website: here.

Don’t miss this chance to explore the cutting-edge capabilities of SENSOCELL in advanced research!

 

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Fig. 1

Time dependence of trap position (top), force signal (middle) and Ca2+ fluorescence signal (bottom) recorded during a membrane tether pulling experiment. The force and Ca2+ ion channel activity signals exhibit negative correlation.

Fig. 2

Force and displacement data for two beads stimulated at frequencies of 4 Hz and 0.25 Hz. The progressive reduction of the beads displacement is in concomitancy with an increase of the applied force and loading rate.

Fig. 1

Schematic representation of the optical tweezers experiment. A fibronectin-coated bead is trapped, brought into contact with the cell membrane and stimulated with oscillations at different frequencies.

Fig.2

Time dependence of trap 1 and trap 2 position (top) and force (bottom) data along the different steps of the described dual tether pulling experiment.

Fig.1

Confocal video of the described dual tether pulling assay performed on a neuron axon. Courtesy of M. Krieg lab (ICFO).

Fig. 1

Time dependence of trap position (top), force signal (middle) and Ca2+ fluorescence signal (bottom) recorded during a membrane tether pulling experiment. The force and Ca2+ ion channel activity signals exhibit negative correlation.

Video 1

Confocal video showing a DVA neuron Ca2+ ion channel activity in a dynamic optical trapping assay. The pulling rate applied to the membrane tether is progressively increased. Scale bar = 5µm. Acquired at 10Hz.