News and Events
Have a look at our latest news:
Delighted to share a new publication recently released that shows another interesting application of SENSOCELL.
In this work, Dr Ahmed et al. analyze the dynamics of a passive colloidal probe immersed in an active bath using Optical tweezers in combination with our force spectroscopy technology .
If you are interested in soft condensed matter and nonlinear rheology do not miss it ! .
Finally! The latest paper from the Neurophotonics & Mechanical Systems Biology group at ICFO has been published in SCIENCE ADVANCES. In this work entitled “An asymmetric mechanical code ciphers curvature-dependent proprioceptor activity”, the mechanical activation of neuronal activity in C. elegans is studied by means of genome editing, modelling and direct force spectroscopy integrated in SENSOCELL optical tweezers.
In this work the authors describe in detail a protocol using SENSOCELL optical tweezers to interrogate the mechanical properties of the cell nucleus inside living cells and that can be extended to the study of other subcellular compartments and organelles. As a representative result, the authors used DNA-Hoechst staining to measure the nucleus deformation upon indentation performed by forces of the order of several hundreds of pN.
In the recent review by Stella Corsetti and Kishan Dholakia: “Optical manipulation: advances for biophotonics in the 21st century”, the IMPETUX’s exclusive technology to measure forces inside living cells and tissues has been considered one of the key advances in the field of optical manipulation of the last decade.
Understanding how cells respond to directly applied forces and to passive mechanical stimuli with SENSOCELL force spectroscopy technology
In this work the authors show how the physicial forces drive mechanosensing by applying dynamic force regimes to cells thought different techniques including Optical Tweezers. o measure the forces applied on cells with Optical Tweezers, they use the SENSOCELL force sensor module: Lunam T-40i.
Stochastic force dynamics generated by a Chlamydomonas microswimmer study with IMPETUX’s exclusive patented technology
Here, we share an interesting publication where the authors study the stochastic force dynamics of a model microswimmer algae (Chlamydomonas reinhardtii). For the experimental work, they directly measured the stochastic forces generated by these algae using an optical trap via the photon momentum method.
Here you will find our upcoming and past events
IMPETUX has been kindly invited to participate at the conference: AQV DAYS 2022 : QUANTITATIVE APPROACHES TO LIVING SYSTEMS organized by the Institute Jacques Monod (France). There, we will be able to meet researchers tackling biological questions with methods coming from physics, chemistry, engineering or other sciences. And, don’t tell anybody, but there will be a live demo session of our SENSOCELL system during the conference!
IMPETUX will be at the MBI 3M 2021. We will show the advantages of our patented direct force spectroscopy technology and explain how we overcome the classical limitations of optical tweezers turning them into a high-level tool for mechanobiology . Want to join us ?
Would you like a DEMO?
Download SENSOCELL brochure