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New protocol for the study of subcellular mechanics in confinement

New protocol for the study of subcellular mechanics in confinement

In this work the authors describe in detail a protocol using SENSOCELL optical tweezers to interrogate the mechanical properties of the cell nucleus inside living cells and that can be extended to the study of other subcellular compartments and organelles. As a representative result, the authors used DNA-Hoechst staining to measure the nucleus deformation upon indentation performed by forces of the order of several hundreds of pN.

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Key advances in optical manipulation for biophotonics

Key advances in optical manipulation for biophotonics

In the recent review by Stella Corsetti and Kishan Dholakia: “Optical manipulation: advances for biophotonics in the 21st century”, the IMPETUX’s exclusive technology to measure forces inside living cells and tissues has been considered one of the key advances in the field of optical manipulation of the last decade.

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Here you will find our upcoming and past events

Next stop : EUROPEAN SOUTH ATLANTIC BIOPHYSICS CONGRESS ESAB2024

Next stop : EUROPEAN SOUTH ATLANTIC BIOPHYSICS CONGRESS ESAB2024

IMPETUX will showcase its advanced SENSOCELL optical tweezers at #ESAB2024! Explore how our technology enhances force measurements and mechanical characterization for in vitro, ex vivo, and in vivo samples, revealing insights into cell membrane mechanics, intracellular microrheology, and stress-relaxation tests

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