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Capturing the complex active and passive material state of the cytoplasm using optical tweezers: Here, we share an interesting preprint from Dr. Betz’s group at the Center for Molecular Biology of Inflammation from the Münster University and the Third Institute...
The characterization of cell membrane elasticity as a new potential biomarker for leukemia cells with IMPETUX technology
Characterizing cell membrane elasticity: Researchers from the Optics Research Unit at De La Salle University and AIST-Osaka University have recently published and study where they have used a customized optical trapping system from IMPETUX to characterize cell...
To deep more into what the IMPETUX technology users are achieving, here we share a list of their latest publications:
Ion Andreu, Bryan Falcones, Sebastian Hurst, Nimesh Chahare, Xarxa Quiroga, Anabel-Lise Le Roux, Zanetta Kechagia, Amy E.M. Beedle, Alberto Elósegui-Artola, Xavier Trepat, Ramon Farré, Timo Betz, Isaac Almendros, Pere Roca-Cusachs
This work provides a unifying mechanism to understand how cells respond not only to directly applied forces, but also to passive mechanical stimuli such as tissue rigidity or ECM ligand distribution.
To deep into the details of this interesting work have a look at the article here.
Stochastic force dynamics of the model microswimmer Chlamydomonas reinhardtii: Active forces and energetics
Corbyn Jones, Mauricio Gomez, Ryan M. Muoio, Alex Vidal, Anthony Mcknight, Nicholas D. Brubaker, Wylie W. Ahmed.
In this work, the authors use a customized optical trapping system from IMPETUX to study the stochastic force dynamics of a model microswimmer algaes (Chlamydomonas reinhardtii). In particular, they directly measure the stochastic forces generated by the algaes using an optical trap via the photon momentum method.
Intracellular softening and fluidification reveals a mechanical switch of cytoskeletal material contributions during division
Sebastian Hurst, Bart E. Vos, Timo Betz
This article is a preprint
In this work, the authors use optical tweezers to show intracellular softening, fluidification and decrease of active forces in mitosis that is mediated by a surprising role switch between microtubules and actin.
Impetux's force sensor is used to measure the cytoplasm's fluidity and stiffness changes of dividing cells.
It is the first time that the cell mechanics is characterized during mitosis from the inside
Mechanical Stretch Inhibition Sensitizes Proprioceptors to Compressive Stresses
Ravi Das, Li-Chun Lin, Frederic Català-Castro, Nawaphat Malaiwong, Neus Sanfeliu, Montserrat Porta-de-la-Riva, Aleksandra Pidde, Michael Krieg.
This article is a preprint.
In this work, researchers used our SENSOCELL Optical Tweezers platform in combination with Confocal microscopy to study neuron Ca2+ dynamics during axon membrane tether extrusion experiments.
The nucleus measures shape deformation for cellular proprioception and regulates adaptive morphodynamics
V. Venturi, F. Pezzano, F. Català-Castro, H.- M. Häkkinen, S. Jiménez-Delgado, M. Colomer-Rosell, M. Marro-Sánchez, Q. Tolosa-Ramon, S. Paz-López, M. A. Valverde, P. Loza-Alvarez, M. Krieg, S. Wieser and V. Ruprecht
For additional information, have a look at:
In-vitro study of monocytic THP-1 leukemia cell membrane elasticity with a single-cell microfluidic-assisted optical trapping system
R. Ombid, G. Oyong, E. Cabrera, W. Espulgar, M. Saito, E. Tamiya, and R. Pobre
In this study, the authors used a customized optical trapping system from IMPETUX to characterize cell membrane elasticity as a new potential biomarker for leukemia cells, comparing measurements for cells treated with anti-cancer drugs and untreated cells.
Optical Force Sensing with Cylindrical Microcontainers
R. Meissner, N. Oliver and C.Denz
F.Català, F. Marsà, M. Montes Usategui, A. Farré & E. Martín-Badosa
Frederic Català, Ferran Marsà, Mario Montes-Usategui, Arnau Farré and Estela Martín-Badosa
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